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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RCC1 All Species: 28.18
Human Site: Y323 Identified Species: 51.67
UniProt: P18754 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18754 NP_001041659.1 421 44969 Y323 Y S L G R A E Y G R L G L G E
Chimpanzee Pan troglodytes XP_001152659 421 44920 Y323 Y S L G R A E Y G R L G L G E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544458 630 67681 Y532 Y S L G R A E Y G R L G L G E
Cat Felis silvestris
Mouse Mus musculus Q8VE37 421 44912 Y323 Y S L G R A E Y G R L G L G E
Rat Rattus norvegicus NP_001121661 421 45093 Y323 Y S L G R A E Y G R L G L G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_427366 194 21051 P98 V L L Q L N V P V V K I V S G
Frog Xenopus laevis P25183 424 45052 Y328 Y S L G R A E Y G R L G L G E
Zebra Danio Brachydanio rerio Q6NYE2 495 54133 T386 F F W G V T N T S R E S T M Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25171 547 58832 Y322 S V V G R P E Y G R L G L G D
Honey Bee Apis mellifera XP_394158 439 46956 R336 M G R K E Y G R L G L G S N C
Nematode Worm Caenorhab. elegans Q18211 569 61466 D452 H V V I L G S D G K V F A M G
Sea Urchin Strong. purpuratus XP_001191815 424 45249 R328 I G R T N Y G R L G L G E D C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P21827 482 52995 Y372 P K D N L P E Y T Y K D V H G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 64.7 N.A. 93.8 93.3 N.A. N.A. 37 75.9 22.2 N.A. 29 45.5 29.5 52.8
Protein Similarity: 100 99.7 N.A. 65.8 N.A. 96.9 96.6 N.A. N.A. 42 85.6 40 N.A. 43.6 63 42.5 70.7
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 6.6 100 13.3 N.A. 66.6 13.3 6.6 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 13.3 100 20 N.A. 80 13.3 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 47 0 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % C
% Asp: 0 0 8 0 0 0 0 8 0 0 0 8 0 8 8 % D
% Glu: 0 0 0 0 8 0 62 0 0 0 8 0 8 0 47 % E
% Phe: 8 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 16 0 62 0 8 16 0 62 16 0 70 0 54 24 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 8 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 8 0 8 0 0 0 0 0 8 16 0 0 0 0 % K
% Leu: 0 8 54 0 24 0 0 0 16 0 70 0 54 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % M
% Asn: 0 0 0 8 8 8 8 0 0 0 0 0 0 8 0 % N
% Pro: 8 0 0 0 0 16 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 16 0 54 0 0 16 0 62 0 0 0 0 0 % R
% Ser: 8 47 0 0 0 0 8 0 8 0 0 8 8 8 0 % S
% Thr: 0 0 0 8 0 8 0 8 8 0 0 0 8 0 0 % T
% Val: 8 16 16 0 8 0 8 0 8 8 8 0 16 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 47 0 0 0 0 16 0 62 0 8 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _